ABOUT
Hong-Wen Tang
Assistant Professor
Ph.D.
Institute of Biochemistry, National Taiwan University
I am currently an Assistant Professor at Duke-NUS. My laboratory was commissioned in December 2020 and has employed molecular, biochemical, and genetic approaches to study the roles of RNA metabolism in muscle homeostasis under different physiological and pathological conditions. In these years, we have built up a strong lab with members having diverse expertise and experience in fly, mouse, and cellular work.
- Harvard Medical School, Postdoctoral fellow, RNA metabolism, 2014-2020
- Human Frontier Science Program (HFSP) fellow, 2015
- Assistant Professor, Cancer & Stem Cell Biology Program, Duke-NUS Medical School,2020-present
- Adjoint Principal Investigator, Division of Cellular and Molecular Research, National Cancer Center Singapore, 2021-present
OUR TEAM
Kah Yong Goh
Research Fellow
Ph.D.
University of Alabama (UAB), Birmingham
During my graduate studies, I investigated how mitochondrial dysfunction and oxidative stress drive pathogenesis in cardiovascular disease. After graduation, I pursued my first post-doctoral fellowship at National Cancer Center Singapore (NCCS) to study the effects of targeted therapies on cancer. Currently, I'm researching the role of autophagy during tumorigenesis and am inspired to develop new therapeutic strategies targeting cancer.
Gopal Krishnan Priyadarshini
Research Fellow
Ph.D.
The University of Western Australia, Perth
My Phd research was based on identifying Rab proteins as potent regulators of the PI3K/mTOR signalling axis and regulating these Rab proteins to reverse the cancerous phenotype in aggressive breast cancer. I have a keen interest in signalling mechanisms and am currently working on uncovering new regulators in both sarcopenia and cancer cachexia, utilizing Drosophila and mouse as model system
Qian Gou
Research Fellow
Ph.D.
Jiangsu University, China
In my PhD study, I identifed that ING4 acts as an autophagy receptor to induce PD-L1 autophagic degradation and inhibits NSCLC tumor immune escape. My present project is to investigate the regulative mechanism of autophagy and muscle aging.
Wen Xing Lee
Phd Student
Ph.D. (In Progress)
Duke-NUS Medical School, Singapore
I am currently a graduate student in the lab. Prior to joining the lab as a student, I worked in this lab as a research assistant and my main project focused on identifying regulators of muscle atrophy during the process of aging. I am really interested in tissue-tissue crosstalks, and for my PhD work, I will be understanding regulators of muscle atrophy during the process of ageing as well as during cancer cachexia.
Shi Chee Ong
Research Assistant
Bachelor
National University of Singapore (NUS), Singapore
I have a deep interest in research and a genuine curiosity for uncovering how our bodies work, especially as we age. My current work looks into the molecular mechanisms behind sarcopenia, a condition where muscle mass and strength gradually decline with age. As populations around the world grow older, understanding the biology behind this condition feels especially meaningful.
Priscillia Choy
Research Assistant
Bachelor (Hons)
International Medical University (IMU), Malaysia
Research is interesting and challenging, but I always enjoy myself during the experiments as it allowed me to gain deeper understanding on the molecular biology. My current project is focusing on the identification of novel regulators controlling muscle stem cells in sarcopenia and I am excited to be a part of an adventure that will change the face of the future.
Visiting research fellow
Assistant Professor Dr Wang Hua Xin
University of Jinan, Shandong (China)
Research internship student
Lewin Raymarc Roldan Turqueza
National University of Singapore (NUS)
Weiyi Jiang
Nanjing Medical University, Nanjing (China)